Wednesday, September 5, 2012

Books and JavaScript stored in DNA molecules

Books and JavaScript stored in DNA molecules - tech - 16 August 2012 - New Scientist@import "/css/gridmain.css"; @import "/css/article.css";@import "/css/comlist.css";@import "/data/images/ns/haas/haas.css";/* specific to this article view */#maincol {border-top:solid #A7A7A7 1px; padding-top:15px;}/* Basic commenting CSS*/.combx {margin:10px 0 0 0;padding:10px 20px 10px 10px;}#compnl {border-top:solid #A7A7A7 1px;}/* comment styles for article page only *//* form styles */#comform {margin:20px 50px 20px 10px;}#comform label{width: 90px;text-align: right;}#comform div.userhelp {margin:0 0 2px 115px;}#comform input.textinput, #comform textarea {width:300px;}#comform div.floatclear, #comformlogin div.floatclear {margin-bottom:10px;}#comform input#comcancel{margin:0 10px 0 0;}#comform input#compreview{margin:0 10px 0 0;}#comform textarea {height:95px;}#comformlogin {margin:20px 100px 20px 100px;}#comformlogin label{width: 120px;}#comformlogin input.textinput {width:150px;}#snv_tech a {background: url('/img/bg/snv_tech.jpg') no-repeat; color:#fff;}/* article social media */#sharebtns {width:440px; margin-left:10px; margin-bottom:20px; padding:15px 0 15px 10px; background:#F2F2F2;}#sharebtns div.floatleft {margin-right:10px;}#sharebtns .stumble {margin-top:1px;}.grpTools img {margin-right:8px; margin-top:9px;}#fblike {margin-top:41px;} Subscribe nowNew ScientistTech    Log in

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Books and JavaScript stored in DNA molecules19:00 16 August 2012 byDouglas Heaven Forget flash – the computers of the future might store data in DNA. George Church of the Wyss Institute at Harvard University and colleagues have encoded a 53,400-word book, 11 JPG images and a JavaScript program – amounting to 5.27 million bits of data in total – into sequences of DNA. In doing so, they have beaten the previous record set by J. Craig Venter's team in 2010 when they encoded a 7920-bit watermark in their synthetic bacterium.

DNA is one of the most dense and stable media for storing information known. In theory, DNA can encode two bits per nucleotide. That's 455 exabytes – roughly the capacity of 100 billion DVDs – per gram of single-stranded DNA, making it five or six orders denser than currently available digital media, such as flash memory. Information stored in DNA can also be read thousands of years after it was first laid down.

Until now, however, the difficulty and cost involved in reading and writing long sequences of DNA has made large-scale data storage impractical. Church and his team got round this by developing a strategy that eliminates the need for long sequences. Instead, they encoded data in distinct blocks and stored these in shorter separate stretches.

The strategy is exactly analogous to data storage on a hard drive, says co-author Sriram Kosuri, where data is divided up into discrete blocks called sectors.

The team has also applied their strategy in practice. They converted a JavaScript program, and a book co-written by Church, into bit form. They then synthesised DNA to repeat that sequence of bits, encoding one bit at every DNA base. The DNA bases A or C encoded a '0', while G and T encoded a '1'.

Because the DNA is synthesised as the data is encoded, the approach doesn't allow for rewritable data storage. A write-only DNA molecule is still suitable for long-term archival storage, though. "I don't want to say [rewriting is] impossible," says Kosuri, "but we haven't yet looked at that."

But the result does show that DNA synthesis and sequencing technologies have finally progressed to the stage where integrating DNA sequence information into a storage medium is a real possibility, says Dan Gibson at the J. Craig Venter Institute in La Jolla, California, who was part of Venter's team in 2010. "Cost, speed and instrument size currently make this impractical for general use, but the field is moving fast, and the technology will soon be cheaper, faster and smaller," he says.

Science, DOI:10.1126/science.293.5536.1763c

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Is This The First Time This Has Been Done?Sat Aug 18 09:41:07 BST 2012 by ullrich fischer

Has anyone looked for text in patterns of DNA within "Junk" sequences in living organisms to see if maybe there was a species of (say) intelligent dinosaurs who left the history of their civilization before the asteroid wiped them out? ... maybe in chicken DNA ?

login and replyreport this commentIs This The First Time This Has Been Done?Mon Aug 20 23:11:39 BST 2012 by Paul G

It goes without saying of course that the intelligent dinosaurs would have encoded their history using ASCII characters and the English language so it should be easy peasy to look for it.

login and replyreport this commentIs This The First Time This Has Been Done?Thu Aug 23 10:53:43 BST 2012 by Eric Kvaalen

If they were smart, they could make pictures like the http://en.wikipedia.org/wiki/Arecibo_message. A series of pictures could be used to teach us their language.

But maybe they didn't think of that...

login and replyreport this commentIs This The First Time This Has Been Done?Sun Aug 26 23:39:34 BST 2012 by ullrich fischer

Ascii is such an obvious way to encode text that surely the dinosaurs would have stumbled upon it. Also, everyone knows that if you shout at a non-english speaking intelligent being loudly enough in English, they will understand you. :)

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